Early Development Trials

Colorful Patients Room

Vince & Associates Clinical Research focuses on Early Phase Clinical Development. This unique focus allows us to collect quality data while establishing early efficacy in study volunteers.

Overnight stays range from a few days to over a month and allows us to monitor volunteer safety during the collection of important scientific data.

Diverse Range of Studies

  • Human Abuse Liability and Substance Abuse
  • Phase I – II Proof-of-Concept (POC)
  • Adaptive Design Studies: Healthy Normal Volunteer and Patient Populations
  • Bioavailability/Bioequivalence (BA/BE)
  • Drug-Drug Interaction
  • First-in-Human (FIH)
  • Biologics/Biosimilars
  • Single Ascending Dose (SAD)
  • Multiple Ascending Dose (MAD)
  • Pharmacokinetics/Pharmacodynamics
  • Dose-Ranging and Tolerability
  • Food Effect
  • Early Precision QT
  • TQT
  • Smoking and Vaping Evaluation

Commitment to Safety

Vince & Associates has established a well-documented commitment to safety throughout the Kansas City and Pharmaceutical communities by utilizing the Physician Research Model®. Because we focus on complex early phase clinical trials, increased in-house monitoring is required to ensure subject safety.

At Vince & Associates, we know that early stage clinical trials are both critical and important to our biopharmaceutical clients. This is especially true when utilizing adaptive trial designs to establish and prove drug efficacy early in development. Additional safety procedures to ensure and protect subject well-being include:

  • 24/7 Advanced Cardiac Life Support provider coverage on site, mitigating risk with sensitive subject population
  • Certification of all clinical staff in Basic Cardiac Life Support
  • Adaptive Clinical Pharmacology Unit (CPU) for complex trials with challenging populations
  • 24/7 notification to Investigators of all Adverse Events
  • Daily assessment of subjects by an Investigator
  • Multiple Crash Carts onsite
  • Scenario-based Employee Response Training
  • 32 Channel Cardiac Telemetry and Pulse Oximetry
  • 52 strategically placed Nurses Call/Panic Buttons
  • 24/7 video surveillance and controlled access throughout the facility